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There are 19 twelve-letter words containing 2A, C, E and Q

ACQUAINTANCEacquaintance n. (Uncountable) A state of being acquainted with a person; originally indicating friendship, intimacy…
acquaintance n. (Countable) A person or persons with whom one is acquainted.
acquaintance n. (Uncountable) Such people collectively; one’s circle of acquaintances (with plural concord).
ACQUITTANCEDacquittanced v. Simple past tense and past participle of acquittance.
ACQUITTANCE v. (Shakespeare) to acquit or clear.
ACQUITTANCESacquittances n. Plural of acquittance.
ACQUITTANCE v. (Shakespeare) to acquit or clear.
AQUACEUTICALAQUACEUTICAL n. a method of delivering food supplements.
AQUACULTURESaquacultures n. Plural of aquaculture.
AQUACULTURE n. the practice of using the sea, lakes etc. for fish-farming, also AQUICULTURE.
EQUIBALANCEDequibalanced v. Simple past tense and past participle of equibalance.
EQUIBALANCE v. to balance equally.
EQUIBALANCESequibalances v. Third-person singular simple present indicative form of equibalance.
EQUIBALANCE v. to balance equally.
INADEQUACIESinadequacies n. Plural of inadequacy.
INADEQUACY n. the state of being inadequate.
LACQUERWARESlacquerwares n. Plural of lacquerware.
LACQUERWARE n. craft goods made from lacquer.
MACABERESQUEmacaberesque adj. Macabre.
macaberesque n. The danse macabre, or some similar performance or imagery.
MACABERESQUE adj. somewhat macaber.
PREACQUAINTSpreacquaints v. Third-person singular simple present indicative form of preacquaint.
PREACQUAINT v. to acquaint beforehand.
QUACKSALVERSquacksalvers n. Plural of quacksalver.
quack-salvers n. Plural of quack-salver.
QUACKSALVER n. (archaic) a quack.
QUADRAPLEGICQUADRAPLEGIC n. one suffering from quadriplegia, paralysis of both arms and both legs, also QUADRIPLEGIC.
QUADRATRICESquadratrices n. Plural of quadratrix.
QUADRATRIX n. a curve by which a circle may be squared.
QUARTERBACKSquarterbacks n. Plural of quarterback.
quarterbacks v. Third-person singular simple present indicative form of quarterback.
QUARTERBACK v. to direct the offensive play of (as a football team).
RACQUETBALLSracquetballs n. Plural of racquetball.
RACQUETBALL n. a game similar to handball that is played on a 4-walled court with a short-handled racket and a larger ball.
REACQUAINTEDreacquainted v. Simple past tense and past participle of reacquaint.
REACQUAINT v. to acquaint again.
SQUIREARCHALsquirearchal adj. Of or pertaining to squirearchy.
SQUIREARCHAL adj. relating to a squirearchy, also SQUIRARCHAL, SQUIRARCHICAL, SQUIREARCHICAL.
UNACQUAINTEDunacquainted adj. Not acquainted, unfamiliar (with someone or something).
unacquainted adj. (Obsolete) Not usual; unfamiliar; strange.
UNACQUAINTED adj. not acquainted.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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