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There are 4 seven-letter words containing A, D, S and 2U

ARDUOUSarduous adj. Needing or using up much energy; testing powers of endurance.
arduous adj. (Obsolete) burning; ardent.
arduous adj. Difficult or exhausting to traverse.
CARDUUSCarduus prop.n. A taxonomic genus within the family Asteraceae – many thistles native to the Old World.
CARDUUS n. (Shakespeare) a thistle.
SUBDUALsubdual n. An act of subduing; a successful defeat.
SUBDUAL n. the act of subduing.
UPHAUDSUPHAUD v. (Scots) to maintain, warrant.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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