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There are 8 eight-letter words containing 2A, C, T and X

ATARAXICataraxic adj. Of or pertaining to ataraxia or ataraxy.
ataraxic adj. (Pharmacology) ataractic; tranquilizing.
ataraxic n. (Pharmaceutical) An ataractic or tranquilizing agent.
CHATEAUXchateaux n. Plural of chateau.
châteaux n. Plural of château.
CHATEAU n. (French) a large country house.
CURTALAXcurtal-ax n. Alternative form of curtal-axe.
CURTALAX n. a short broadsword, also CURTAXE, CURTALAXE.
EXCAVATEexcavate v. (Transitive) To make a hole in (something); to hollow.
excavate v. (Transitive) To remove part of (something) by scooping or digging it out.
excavate v. (Transitive) To uncover (something) by digging.
MAXICOATmaxicoat n. A woman’s long coat.
MAXICOAT n. a long coat.
TAXIARCHtaxiarch n. (Historical, Ancient Greece) An Athenian military officer commanding a certain division of an army.
TAXIARCH n. an Athenian military officer commanding a certain division of an army.
TAXICABStaxicabs n. Plural of taxicab.
taxicabs v. Third-person singular simple present indicative form of taxicab.
TAXICAB n. automobile for hire.
TOXOCARAToxocara prop.n. A taxonomic genus within the family Toxocaridae – certain parasitic nematodes that cause toxocariasis in humans.
TOXOCARA n. a kind of parasitic worm found in the intestines of dogs and cats.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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