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There are 2 eight-letter words containing 2A, D and 2U

LAUDANUMlaudanum n. A tincture of opium, once widely used for various medical purposes and as a recreational drug.
laudanum v. (Transitive) To add laudanum to (a drink or the like).
laudanum v. (Rare) To cause (a person) to be high on laudanum.
QUAALUDEquaalude n. Alternative letter-case form of Quaalude.
Quaalude prop.n. (Pharmacology) A proprietary name for methaqualone.
Quaalude n. A dose of this drug, sometimes taken recreationally.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org.

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