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There are 7 eight-letter words containing A, 2C, F and T

CALCTUFAcalctufa n. Calcite; calcspar.
calc-tufa n. Tufa.
CALCTUFA n. a rock made of fine volcanic detritus, also TOPH, TOPHE, TUFA.
CALCTUFFcalctuff n. Alternative form of calctufa.
calc-tuff n. Alternative form of calc-tufa.
CALCTUFF n. a general term for all consolidated pyroclastic rock, also TUFF.
CATCHFLYcatchfly n. Any of several unrelated plants that have sticky leaves on which flies become stuck; especially, the…
CATCHFLY n. a name for a species of campion with sticky stems.
CATFACEScatfaces n. Plural of catface.
CATFACE n. a deformity of fruit.
COFACTORcofactor n. A contributing factor.
cofactor n. (Biochemistry) A substance, especially a coenzyme or a metal, that must be present for an enzyme to function.
cofactor n. (Biochemistry) A molecule that binds to and regulates the activity of a protein.
FACTICESfactices n. Plural of factice.
FACTICE n. vulcanized oil, used as substitute for rubber, also FACTIS.
LACTIFIClactific adj. Producing or yielding milk.
LACTIFIC adj. producing milk.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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