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There are 14 eight-letter words containing A, C, M and 2U

ACICULUMaciculum n. (Botany, zoology) A needlelike spine or bristle, specially the seta of an annelid.
ACICULUM n. (Latin) a bristlelike part.
BACULUMSbaculums n. Plural of baculum.
BACULUM n. (Latin) the bone in the penis of certain mammals.
COAGULUMcoagulum n. A mass of coagulated material; a clot or curd.
COAGULUM n. (Latin) a clot.
COUMAROUcoumarou n. The tree Dipteryx odorata, which bears the tonka bean.
coumarou n. The tonka bean itself.
COUMAROU n. (Tupi) the seed of a tropical tree, aka tonka bean.
CUMQUATScumquats n. Plural of cumquat.
CUMQUAT n. (Chinese) any of several small yellow to orange citrus fruits, also KUMQUAT.
CUMULATEcumulate v. (Transitive) To accumulate; to amass.
cumulate v. (Intransitive) To be accumulated.
cumulate adj. Accumulated, agglomerated, amassed.
CURCUMASCURCUMA n. (Arabic) any plant of the genus Curcuma (of the ginger family), esp. one yielding turmeric.
CUSTUMALcustumal n. A survey of a medieval English manor, listing each tenant and the customs under which the tenancy was held.
CUSTUMAL n. a written record or laws and customs.
GUAIACUMguaiacum n. Any of a number of species of tree of the genus Guaiacum, native to the West Indies and parts of the Americas.
guaiacum n. The wood or resin of this tree.
GUAIACUM n. a medicinal resin, also GUAIAC, GUAIOCUM.
GUAIOCUMGUAIOCUM n. a medicinal resin, also GUAIACUM, GUAIAC.
MUSCULARmuscular adj. (Relational) Of, relating to, or connected with muscles.
muscular adj. Brawny, thewy, having strength.
muscular adj. Having large, well-developed muscles.
SAECULUMsaeculum n. A length of time roughly equal to the potential lifetime of a human being or, equivalently, the complete…
SAECULUM n. (Latin) an astronomical or geological age, also SECULUM.
VACUUMEDvacuumed v. Simple past tense and past participle of vacuum.
vacuumed adj. Having been cleaned with a vacuum cleaner; hoovered.
VACUUM v. to operate a cleaner that uses suction.
VASCULUMvasculum n. A container used by botanists to store newly-collected samples.
VASCULUM n. (Latin) a box used to hold plant specimens.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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