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There are 6 eight-letter words containing A, H, I, S and X

ASPHYXIAasphyxia n. Loss of consciousness due to the interruption of breathing and consequent anoxia.
asphyxia n. Loss of consciousness due to the body’s inability to deliver oxygen to its tissues, either by the breathing…
asphyxia n. (Medicine, obsolete) A condition in which an extreme decrease in the concentration of oxygen in the…
CATHEXIScathexis n. (Psychoanalysis) The concentration of libido or emotional energy on a single object or idea.
CATHEXIS n. (Greek) the investment of emotional energy in a thought or idea.
HYPOXIAShypoxias n. Plural of hypoxia.
HYPOXIA n. a deficiency of oxygen in the body tissues, also HYPOXAEMIA, HYPOXEMIA.
PHYLAXISphylaxis n. (Medicine) Protection against infectious disease.
PHYLAXIS n. an inhibiting of infection by the body.
XANTHINSxanthins n. Plural of xanthin.
XANTHIN n. a white substance, structurally related to uric acid, found in muscle tissue, the liver and other organs, also XANTHINE.
XANTHISMxanthism n. (Biology, zoology) A yellowish colouring of pigments in hair, skin, feathers, etc.
XANTHISM n. a condition of skin, fur or feathers in which yellow coloration predominates.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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