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There are 19 eight-letter words containing A, I, P, S and X

APOMIXESapomixes n. Plural of apomixis.
APOMIXIS n. (Greek) nonsexual reproduction, from an apomict or unfertilized ovum.
APOMIXISapomixis n. (Botany) Plant reproduction without fertilization.
apomixis n. (Botany) Plant reproduction without fertilization, meiosis, or the production of gametes.
apomixis n. (Zoology) Animal reproduction in which the egg cell does not undergo meiosis or fertilization.
APRAXIASapraxias n. Plural of apraxia.
APRAXIA n. an inability to perform voluntary bodily movements.
ASPHYXIAasphyxia n. Loss of consciousness due to the interruption of breathing and consequent anoxia.
asphyxia n. Loss of consciousness due to the body’s inability to deliver oxygen to its tissues, either by the breathing…
asphyxia n. (Medicine, obsolete) A condition in which an extreme decrease in the concentration of oxygen in the…
EPITAXESEPITAXIS n. the part of a play in which the main action develops, also EPITASIS.
EPITAXISEPITAXIS n. the part of a play in which the main action develops, also EPITASIS.
EXPIATESexpiates v. Third-person singular simple present indicative form of expiate.
EXPIATE v. to make complete atonement for.
EXPLAINSexplains v. Third-person singular simple present indicative form of explain.
EXPLAIN v. to make clear and understandable.
HYPOXIAShypoxias n. Plural of hypoxia.
HYPOXIA n. a deficiency of oxygen in the body tissues, also HYPOXAEMIA, HYPOXEMIA.
MIXTAPESmixtapes n. Plural of mixtape.
mix␣tapes n. Plural of mix tape.
MIXTAPE n. a compilation of songs from various sources.
PANMIXESPANMIXIS n. (Greek) random mating within a breeding population, also PANMIXIA.
PANMIXISpanmixis n. (Ecology) Panmixia.
PANMIXIS n. (Greek) random mating within a breeding population, also PANMIXIA.
PAXIUBASpaxiubas n. Plural of paxiuba.
PAXIUBA n. (Portuguese) a Brazilian palm with stilt-roots.
PHYLAXISphylaxis n. (Medicine) Protection against infectious disease.
PHYLAXIS n. an inhibiting of infection by the body.
PICKAXESpickaxes n. Plural of pickaxe.
pickaxes v. Third-person singular simple present indicative form of pickax.
pick-axes n. Plural of pick-axe.
PRAXISESpraxises n. Plural of praxis.
PRAXIS n. (Greek) practical use of a branch of learning.
PYREXIASpyrexias n. Plural of pyrexia.
PYREXIA n. (Greek) a fever.
SPADIXESspadixes n. Plural of spadix.
SPADIX n. (Greek) a flower-spike covered by large leaf, as in the arum plant.
SPARAXISsparaxis n. Any of several deciduous perennial flowering herbs, of the genus Sparaxis, from South Africa.
SPARAXIS n. a South African iridaceous plant with starlike flowers and lacerated spathes.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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