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There are 19 twelve-letter words containing 2A, C, R, T and X

CARBOXYLATEDcarboxylated v. Simple past tense and past participle of carboxylate.
carboxylated adj. (Chemistry) Converted into a carboxylic acid, normally by the oxidation of an alcohol or aldehyde.
CARBOXYLATE v. to introduce carboxyl or carbon dioxide into (a compound) with formation of a carboxylic acid.
CARBOXYLATEScarboxylates n. Plural of carboxylate.
CARBOXYLATE v. to introduce carboxyl or carbon dioxide into (a compound) with formation of a carboxylic acid.
CONTRASEXUALcontrasexual adj. (Jungian psychology, of part of the psyche) Having characteristics of the opposite gender.
CONTRASEXUAL n. one who represses the personality traits that most people repress because they are characteristic of the opposite sex.
DEXTROCARDIAdextrocardia n. (Medicine) A congenital abnormality in which the heart is transposed to the right side of the chest.
DEXTROCARDIA n. a condition in which the heart is on the right-hand side of the chest.
EXACERBATINGexacerbating v. Present participle of exacerbate.
exacerbating adj. That exacerbates.
EXACERBATE v. to make more violent, bitter, or severe.
EXACERBATIONexacerbation n. An increase in the severity of something (such as a disease).
EXACERBATION n. the act of exarcebating.
EXCARNATIONSexcarnations n. Plural of excarnation.
EXCARNATION n. the act of excarnating, removing the flesh from.
EXOPARASITICEXOPARASITIC adj. of or like an exoparasite.
EXTRACRANIALextracranial adj. Not intracranial, but outside the cranium.
EXTRACRANIAL adj. situated or occurring outside the cranium.
EXTRAHEPATICextrahepatic adj. Originating or occurring outside the liver.
EXTRAHEPATIC adj. situated or originating outside the liver.
EXTRALOGICALextralogical adj. Outside of the domain of logic.
EXTRALOGICAL adj. not guided or determined by considerations of logic.
EXTRAMUSICALextramusical adj. Apart from and in addition to music.
EXTRAMUSICAL adj. lying outside the province of music.
EXTRANUCLEARextranuclear adj. Outside the nucleus.
extranuclear adj. (Biology) Outside the nucleus but within the cell cytoplasm.
EXTRANUCLEAR adj. situated in or affecting the parts of a cell external to the nucleus.
EXTRAVAGANCEextravagance n. Excessive or superfluous expenditure of money.
extravagance n. Prodigality, as of anger, love, expression, imagination, or demands.
EXTRAVAGANCE n. an instance of excess or prodigality, also EXTRAVAGANCY.
EXTRAVAGANCYextravagancy n. (Archaic, 17-19th centuries) The characteristic of being extravagant.
extravagancy n. (Archaic, 17-19th centuries) A thing that is extravagant.
EXTRAVAGANCY n. an instance of excess or prodigality, also EXTRAVAGANCE.
HEXAMETRICALhexametrical adj. Hexametric; consisting of six metrical feet.
HEXAMETRICAL adj. of verse, written in hexameters, also HEXAMETRAL, HEXAMETRIC.
TOXOCARIASESTOXOCARIASIS n. a disease caused by parasitic worms.
TOXOCARIASIStoxocariasis n. A zoonotic, helminthic infection of humans caused by roundworms of the genus Toxocara.
TOXOCARIASIS n. a disease caused by parasitic worms.
XANTHOCHROIAxanthochroia n. (Pathology) A condition characterized by yellow patches on the skin.
XANTHOCHROIA n. yellowness of the skin.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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