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There are 10 twelve-letter words containing 2A, F and 3S

AFTERGRASSESaftergrasses n. Plural of aftergrass.
after-grasses n. Plural of after-grass.
AFTERGRASS n. the grass that grows after the first crop has been mown; aftermath.
ANTIFASCISMSantifascisms n. Plural of antifascism.
anti-fascisms n. Plural of anti-fascism.
ANTIFASCISM n. opposition to fascism.
ANTIFASCISTSantifascists n. Plural of antifascist.
ANTIFASCIST n. one who opposes fascism.
ASSAFOETIDASASSAFOETIDA n. an acrid gum resin with a strong smell like that of garlic, obtained from certain Asian plants, also ASAFETIDA, ASAFOETIDA, ASSAFETIDA.
FASCIOLIASESfascioliases n. Plural of fascioliasis.
FASCIOLIASIS n. nematode infestation.
FASCIOLIASISfascioliasis n. (Pathology) infestation with liver flukes (of genus Fasciola).
FASCIOLIASIS n. nematode infestation.
FASHIONISTASfashionistas n. Plural of fashionista.
FASHIONISTA n. a follower or setter of fashion, also FASHIONIST.
INFRACLASSESinfraclasses n. Plural of infraclass.
MISFEASANCESmisfeasances n. Plural of misfeasance.
MISFEASANCE n. the performance by a public official of an act that is legally unjustified, harmful, or contrary to law; wrongdoing (used especially of an act in violation of a public trust), also MALFEASANCE.
TRANSFERASEStransferases n. Plural of transferase.
TRANSFERASE n. an enzyme that promotes transfer of a group from one molecule to another.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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