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There are 12 twelve-letter words containing 2A, N, 2T and X

ANTHOXANTHINanthoxanthin n. (Biochemistry) Any of a group of water-soluble flavonoid pigments found in plants.
ANTHOXANTHIN n. a yellow pigment in plants.
ANTIOXIDANTSantioxidants n. Plural of antioxidant.
ANTIOXIDANT n. a substance (as betacarotene or vitamin C) that inhibits oxidation.
ASTAXANTHINSastaxanthins n. Plural of astaxanthin.
AUTOXIDATIONautoxidation n. (Chemistry) A spontaneous oxidation reaction that results in the slow, flameless combustion of a material.
AUTOXIDATION n. oxidation by direct combination with oxygen at ordinary temperatures.
EXANTHEMATICexanthematic adj. Of or pertaining to exanthem.
EXANTHEMATIC adj. of or like an exanthem, a skin eruption, esp. accompanied by fever, also EXANTHEMATOUS.
EXPATIATIONSexpatiations n. Plural of expatiation.
EXPATIATION n. the act of expatiating.
EXPATRIATINGexpatriating v. Present participle of expatriate.
EXPATRIATE v. to banish, exile.
EXPATRIATIONexpatriation n. Voluntary migration from one’s native land to another.
expatriation n. Forced expulsion of from one’s native land to another.
EXPATRIATION n. the act of expatriating.
EXPLANTATIONexplantation n. The act of explanting.
EXPLANTATION n. the act of explanting.
OVERTAXATIONovertaxation n. Excessive taxation.
OVERTAXATION n. excessive taxation.
PORTMANTEAUXportmanteaux n. Plural of portmanteau.
PORTMANTEAU n. (French) a case opening in two parts, used for carrying clothes while traveling, also PORTMANTLE, PORTMANTUA.
XANTHOMATOUSxanthomatous adj. Of or relating to xanthoma or xanthomatosis.
XANTHOMATOUS adj. of or like a xanthoma, a skin disease marked by the development or irregular yellowish patches upon the skin.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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