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There are 13 twelve-letter words containing 2A, 2S, T and X

ASEXUALITIESasexualities n. Plural of asexuality.
ASEXUALITY n. the state of being asexual.
ASPHYXIATORSasphyxiators n. Plural of asphyxiator.
ASPHYXIATOR n. one of who asphyxiates.
ASTAXANTHINSastaxanthins n. Plural of astaxanthin.
EXASPERATERSexasperaters n. Plural of exasperater.
EXASPERATER n. one who exasperates, also EXASPERATOR.
EXASPERATORSexasperators n. Plural of exasperator.
EXASPERATOR n. one who exasperates, also EXASPERATER.
EXOPARASITESexoparasites n. Plural of exoparasite.
EXOPARASITE n. a parasite, such as the flea, that lives on the outer surface of its host.
EXTRAVASATESextravasates v. Third-person singular simple present indicative form of extravasate.
EXTRAVASATE v. in pathology, to exude from a vessel into surrounding tissue; in geology, to erupt.
LAXATIVENESSlaxativeness n. The quality of being laxative.
LAXATIVENESS n. the state of being laxative.
PANSEXUALISTpansexualist adj. (Psychology) Pertaining to or promoting the psychological theory of pansexualism.
pansexualist n. (Psychology) A proponent of the psychological theory of pansexualism.
pansexualist n. (Rare, sometimes derogatory) A person who is attracted, or who is able to experience attraction, to…
STEREOTAXIASSTEREOTAXIA n. the electrical destruction of a small area of brain tissue, using stereotactic methods, to relieve disorders such as epilepsy and Parkinsonism.
TOXOCARIASESTOXOCARIASIS n. a disease caused by parasitic worms.
TOXOCARIASIStoxocariasis n. A zoonotic, helminthic infection of humans caused by roundworms of the genus Toxocara.
TOXOCARIASIS n. a disease caused by parasitic worms.
TRANSSEXUALStranssexuals n. Plural of transsexual.
TRANSSEXUAL n. a person anatomically of one sex but having a strong desire to adopt the physical characteristics and role of a member of the opposite sex, also TRANSEXUAL.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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