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There are 7 twelve-letter words containing A, B, F, M and 2R

FIBROSARCOMAfibrosarcoma n. (Oncology) A fibroblastic sarcoma: a malignant tumor derived from fibrous connective tissue.
FIBROSARCOMA n. a sarcoma formed of spindle-shaped cells in collagenous fibrils.
IMPERFORABLEimperforable adj. Incapable of being perforated.
IMPERFORABLE adj. not able to be perforated.
IRREFORMABLEirreformable adj. That cannot be reformed.
IRREFORMABLE adj. incapable of being reformed.
IRREFORMABLYirreformably adv. Such that it cannot be reformed.
IRREFORMABLE adv. incapable of being reformed.
MYOFIBRILLARmyofibrillar adj. (Anatomy) Of or pertaining to myofibrils.
MYOFIBRILLAR adj. relating to myofibrils.
NEUROFIBROMAneurofibroma n. (Medicine) A benign tumor composed of fibroblasts surrounding nerve cells.
NEUROFIBROMA n. a tumour of the nervous fibre.
UNREFORMABLEunreformable adj. That cannot be reformed.
UNREFORMABLE adj. not reformable.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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