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There are 18 twelve-letter words containing A, C, 2I, R and X

ALEXIPHARMICalexipharmic n. (Pharmacology, chiefly archaic or historical, also figuratively) Synonym of alexipharmac (“a medical…
alexipharmic adj. (Pharmacology, chiefly archaic or historical) Synonym of alexipharmac (“of or pertaining to an alexipharmac;…
ALEXIPHARMIC adj. acting as an antidote to poison.
ANOREXIGENICanorexigenic adj. (Medicine) creating or inducing a state of anorexia.
anorexigenic n. An anorexigenic agent.
ANOREXIGENIC adj. promoting or causing anorexia.
AXISYMMETRICaxisymmetric adj. Exhibiting symmetry around an axis; exhibiting cylindrical symmetry.
axi-symmetric adj. Alternative form of axisymmetric.
AXISYMMETRIC adj. symmetrical in respect to an axis, also AXISYMMETRICAL.
DICARBOXYLICdicarboxylic adj. (Organic chemistry) Having two carboxylic groups.
DICARBOXYLIC adj. containing two carboxyl groups in the molecule.
EXCORIATIONSexcoriations n. Plural of excoriation.
EXCORIATION n. the act of excoriating.
EXCRUCIATINGexcruciating adj. Causing great pain or anguish, agonizing.
excruciating adj. Exceedingly intense; extreme.
EXCRUCIATE v. to inflict intense pain on.
EXCRUCIATIONexcruciation n. Excruciating pain.
EXCRUCIATION n. the act of excruciating.
EXERCITATIONexercitation n. (Rare or obsolete) The exercise or exertion of some power, responsibility, faculty etc.
EXERCITATION n. putting into practice.
EXOPARASITICEXOPARASITIC adj. of or like an exoparasite.
EXORCISTICALexorcistical adj. Relating to exorcism.
EXORCISTICAL adj. relating to exorcism, also EXORCISTIC.
EXTRICATIONSextrications n. Plural of extrication.
EXTRICATION n. the act of extricating.
EXTRINSICALSextrinsicals n. Plural of extrinsical.
EXTRINSICAL n. an extrinsic thing.
INEXTRICABLEinextricable adj. (Of a knot etc) Impossible to untie or disentangle.
inextricable adj. (Of a problem) Impossible to solve.
inextricable adj. (Of a maze etc) Impossible to escape from.
INEXTRICABLYinextricably adv. In an inextricable manner.
inextricably adv. To an inextricable degree.
INEXTRICABLE adv. forming a maze or tangle from which it is impossible to get free.
INTOXICATORSintoxicators n. Plural of intoxicator.
INTOXICATOR n. one who intoxicates.
LUXURIANCIESluxuriancies n. Plural of luxuriancy.
LUXURIANCY n. the state of being luxuriant, also LUXURIANCE.
MIXOBARBARICmixo-barbaric adj. (Archaic) Mixed with barbarous elements.
MIXOBARBARIC adj. part barbaric, part Greek.
TOXOCARIASIStoxocariasis n. A zoonotic, helminthic infection of humans caused by roundworms of the genus Toxocara.
TOXOCARIASIS n. a disease caused by parasitic worms.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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