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There are 3 twelve-letter words containing A, F, 2O and 2U

CAULIFLOROUScauliflorous adj. (Botany) Having flowers on the stem.
CAULIFLOROUS adj. relating to cauliflory, the production of flowers on old stems from dormant buds.
FAUXBOURDONSFAUXBOURDON n. (French) a type of improvised polyphony, popular in England from the 15th century to the Reformation, also FABURDEN.
FLUOROURACILfluorouracil n. (Pharmacology) A fluorine-substituted derivative of uracil C4H3FN2O2 which inhibits DNA synthesis and…
FLUOROURACIL n. a fluorine-containing pyrimidine base used as a neoplastic agent to treat some kinds of cancer.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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