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There are 3 eight-letter words containing A, I, 2N, O and X

ANATOXINanatoxin n. A bacterial toxin (usually an exotoxin) whose toxicity has been weakened or suppressed.
anatoxin n. A powerful neurotoxin, one of many toxins produced by several species of cyanobacterium.
ANATOXIN n. a potent alkaloid toxin derived from a species of cyanobacteria.
ANNEXIONannexion n. (Obsolete) annexation.
ANNEXION n. (archaic) the act of annexing, also ANNEXATION.
OXYANIONoxyanion n. (Chemistry) Any anion derived from an oxyacid.
OXYANION n. an anion containing one or more oxygen atoms bonded to another element (as in the sulphate and carbonate ions).

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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