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There are 20 words containing 2A, 2O and 2U

AUTOGAMOUSautogamous adj. Self-fertilizing.
AUTOGAMOUS adj. self-fertilizing, also AUTOGAMIC.
AUTOMATOUSautomatous adj. Obsolete form of automatic.
AUTOMATOUS adj. like an automaton.
AUTOPHAGOUSautophagous adj. Self-eating; exhibiting autophagy.
AUTOPHAGOUS adj. related to autophagy, sustenance by self-absorption of the tissues of the body.
AUTOPHANOUSautophanous adj. (Rare) Producing its own light.
AUTOPHANOUS adj. self-luminous.
GLAUCOMATOUSglaucomatous adj. Having the nature of glaucoma.
GLAUCOMATOUS adj. affected by glaucoma.
AUTOCEPHALOUSautocephalous adj. (Christianity, of a church) Fully independent of the authority of any other church.
autocephalous adj. (Christianity, of a bishop) Presiding over an autocephalous church.
autocephalous adj. (Comparable) Independent; self-directed.
GRANULOMATOUSgranulomatous adj. (Pathology) Of, pertaining to, or characterised by granulomata.
GRANULOMATOUS adj. of or like a granuloma, a localized collection of granulation tissue.
SAUROGNATHOUSsaurognathous adj. (Zoology) having the bones of the palate arranged as in saurians, the vomer consisting of two lateral…
SAUROGNATHOUS adj. having a lizard-like arrangement of the palate-bones (as e.g. woodpeckers).
AQUIFOLIACEOUSaquifoliaceous adj. (Botany) Belonging to the Aquifoliaceae.
AQUIFOLIACEOUS adj. belonging to the holly family.
MONOUNSATURATEmonounsaturate n. A monounsaturated oil, or fatty acid.
mono-unsaturate n. Alternative spelling of monounsaturate.
MONOUNSATURATE n. a monounsaturated compound.
PORTULACACEOUSportulacaceous adj. (Botany) Of or relating to the family Portulacaceae of plants including the spring beauty.
PORTULACACEOUS adj. belonging to the leek family.
SIMAROUBACEOUSsimaroubaceous adj. (Botany) Belonging to the family Simaroubaceae of tropical and subtropical trees.
SIMAROUBACEOUS adj. belonging to the Simarubaceae, a family of tropical trees related to the Rutaceae, also SIMARUBACEOUS.
ULTRAGLAMOROUSultraglamorous adj. Extremely glamorous.
ULTRAGLAMOROUS adj. extremely glamorous.
AUTOINOCULATIONautoinoculation n. Inoculation into oneself (as of modified cells).
autoinoculation n. (Pathology) The spread of a disease to another part of the body via inoculation.
AUTOINOCULATION n. self-inoculation.
AUTOTRANSFUSIONautotransfusion n. (Medicine) A blood transfusion in which a person receives their own blood, extracted previously.
AUTOTRANSFUSION n. the return of autologous blood to the patient's own circulatory system.
BIOACCUMULATIONbioaccumulation n. (Biology) The process by which substances accumulate in the tissues of living organisms; used especially…
BIOACCUMULATION n. accumulation in a biological system over time.
DEUTERANOMALOUSdeuteranomalous adj. Having or relating to deuteranomaly.
DEUTERANOMALOUS adj. exhibiting partial loss of green color vision so that an increased intensity of green is required in a mixture of red and green to match a given yellow.
MONOUNSATURATEDmonounsaturated adj. (Chemistry, of an organic compound) having a single double or triple bond.
MONOUNSATURATED adj. containing one double or triple bond per molecule.
MONOUNSATURATESmonounsaturates n. Plural of monounsaturate.
mono-unsaturates n. Alternative spelling of monounsaturates.
mono-unsaturates n. Plural of mono-unsaturate.
ROUNDABOUTATIONROUNDABOUTATION n. going round and round.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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