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There are 14 words containing A, 2L, 2S and X

CLIMAXLESSclimaxless adj. Without a climax.
CLIMAXLESS adj. without a climax.
PLEXIGLASSplexiglass n. Polymethyl methacrylate (polymer of methyl methacrylate), a tough transparent plastic used sometimes in lieu of glass.
Plexiglass n. Misspelling of Plexiglas.
PLEXIGLASS n. acrylic plastic sheets.
SMALLPOXESsmallpoxes n. Plural of smallpox.
SMALLPOX n. a virus disease.
LEXICALISESlexicalises v. Third-person singular simple present indicative form of lexicalise.
LEXICALISE v. to put into a lexicon, also LEXICALIZE.
PLEXIGLASSESplexiglasses n. Plural of plexiglass.
PLEXIGLASS n. acrylic plastic sheets.
EXHAUSTLESSLYexhaustlessly adv. Without running out or coming to an end.
EXHAUSTLESS adv. inexhaustible.
POLYSILOXANESpolysiloxanes n. Plural of polysiloxane.
POLYSILOXANE n. any of a number of polymers which are the basis of silicone chemistry.
SEXAGESIMALLYsexagesimally adv. In the sexagesimal system.
SEXAGESIMAL adv. relating to, or based on, sixty.
XYLOBALSAMUMSXYLOBALSAMUM n. the dried twigs, or the wood, of the balm of Gilead tree.
ISOALLOXAZINESisoalloxazines n. Plural of isoalloxazine.
ISOALLOXAZINE n. a yellow solid that is the precursor of various flavins, such as riboflavin.
PSYCHOSEXUALLYpsychosexually adv. In a psychosexual manner or context.
PSYCHOSEXUAL adv. of or relating to the mental, emotional, and behavioral aspects of sexual development.
SUBMAXILLARIESSUBMAXILLARY n. the submaxillary gland.
XIPHIPLASTRALSXIPHIPLASTRAL n. a type of chelonian.
LEXICALISATIONSlexicalisations n. Plural of lexicalisation.
LEXICALISATION n. the realization of a meaning in a single word or morpheme rather than in a grammatical construction, also LEXICALIZATION.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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