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There are 10 ten-letter words containing 2A, N, O, P, T and U

AMPUTATIONamputation n. Surgical removal of all or part of a limb, etc.
amputation n. The loss of a limb, etc. through trauma.
AMPUTATION n. the act of amputating.
ANATROPOUSanatropous adj. (Botany, of an ovule) Having an inverted nucleus, whose apex points to the base.
ANATROPOUS adj. of an ovule, inverted so that the micropyle is next to the stalk.
CANTALOUPEcantaloupe n. A melon of species Cucumis melo subsp. melo with sweet orange flesh, with numerous cultivars in several…
cantaloupe n. An orange colour, like that of cantaloupe flesh.
CANTALOUPE n. (Italian) a small musk melon with a ribbed skin, also CANTALOUP.
CANTALOUPScantaloups n. Plural of cantaloup.
CANTALOUP n. (Italian) a small musk melon with a ribbed skin, also CANTALOUPE.
NATUROPATHnaturopath n. (Alternative medicine) A practitioner of naturopathy, a nature healer.
NATUROPATH n. a person who practises naturopathy.
PAPULATIONpapulation n. (Medicine) The formation of papules.
PAPULATION n. the development of papillae or pimples.
PARAMOUNTSparamounts n. Plural of paramount.
PARAMOUNT n. an overlord; a supreme ruler or proprietor.
PORTMANTUAportmantua n. Obsolete form of portmanteau (“case”).
PORTMANTUA n. (obsolete) a portmanteau, also PORTMANTEAU, PORTMANTLE.
UNPASTORALunpastoral adj. Not pastoral.
UNPASTORAL adj. not pastoral.
VAPULATIONvapulation n. (Obsolete) The act of beating or whipping.
VAPULATION n. the act of beating or whipping.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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