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There are 3 ten-letter words containing A, C, H, 2L, M and O

ALCOHOLISMalcoholism n. A chronic disease caused by compulsive and uncontrollable consumption of alcoholic beverages, leading…
alcoholism n. (Pathology) Acute alcohol poisoning.
ALCOHOLISM n. continued excessive or compulsive use of alcoholic drinks.
CHLORALISMchloralism n. (Medicine) A morbid condition of the system resulting from excessive use of chloral.
CHLORALISM n. a morbid condition of the system resulting from excessive use of chloral.
MELANCHOLYmelancholy n. (Historical) Black bile, formerly thought to be one of the four "cardinal humours" of animal bodies.
melancholy n. Great sadness or depression, especially of a thoughtful or introspective nature.
melancholy adj. (Literary) Affected with great sadness or depression.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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