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There are 3 twelve-letter words containing 4A, E, N and P

ANAPAESTICALanapaestical adj. Anapestic.
ANAPAESTICAL adj. in the form of an anapaest, two short metrical syllables followed by one long one.
ASPARAGINASEasparaginase n. (Biochemistry) An enzyme that catalyzes the hydrolysis of asparagine to aspartic acid, used in chemotherapy.
ASPARAGINASE n. an enzyme that causes asparagine to hydrolyse to aspartic acid and ammonia.
PARALANGUAGEparalanguage n. (Linguistics) The non-verbal elements of speech, and to a limited extent of writing, used to modify…
PARALANGUAGE n. nonverbal elements which affect meaning of speech, as intonation, etc.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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