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There are 16 twelve-letter words containing 3A, C, E, O and S

ACANTHACEOUSacanthaceous adj. (Botany): Of, pertaining to, or resembling, a member of the Acanthaceae family.
acanthaceous adj. Armed with prickles, as a plant.
ACANTHACEOUS adj. prickly; of the Acanthaceae.
ACETONAEMIASACETONAEMIA n. an abnormal increase of ketone bodies in the blood, also ACETONEMIA.
ACHAENOCARPSachaenocarps n. Plural of achaenocarp.
ACHAENOCARP n. any dry indehiscent fruit.
AEROSTATICALaerostatical adj. Of or relating to aerostatics; pneumatic.
aerostatical adj. Aeronautic.
AEROSTATICAL adj. relating to aerostatics, also AEROSTATIC.
AGARICACEOUSagaricaceous adj. (Mycology) Belonging to the Agaricaceae.
AGARICACEOUS adj. belonging to the agaric family of fungi.
AUTOCATALYSEautocatalyse v. Alternative spelling of autocatalyze.
AUTOCATALYSE v. to effect autocatalysis, also AUTOCATALYZE.
CALCEOLARIAScalceolarias n. Plural of calceolaria.
CALCEOLARIA n. any plant of the South American genus Calceolaria, the plants of which are largely cultivated for the beauty of their slipper-like flowers.
GALACTOSEMIAgalactosemia n. (Medicine) A genetic metabolic disorder characterized by an inability to metabolize galactose properly.
galactosemia n. The presence of galactose in the blood.
GALACTOSEMIA n. the presence of galactose in the blood, also GALACTOSAEMIA.
OSTEOMALACIAosteomalacia n. (Medicine) A softening of adult bones due to inadequate mineralization; the adult equivalent of rickets.
osteo-malacia n. Alternative spelling of osteomalacia.
OSTEOMALACIA n. softening of the skull due to calcium deficiency.
OXALACETATESoxalacetates n. Plural of oxalacetate.
OXALACETATE n. a salt or ester of oxaloacetic acid, also OXALOACETATE.
PANDANACEOUSpandanaceous adj. (Botany) Of or relating to the plant family Pandanaceae.
PANDANACEOUS adj. belonging to the Pandanaceae, a family of trees and bushes related to the bulrushes and bur-reeds.
PARACETAMOLSparacetamols n. Plural of paracetamol.
PARACETAMOL n. a mild analgesic and antipyretic drug, often recommended instead of aspirin.
PLATANACEOUSplatanaceous adj. (Botany) Belonging to the family Platanaceae of plane trees.
PLATANACEOUS adj. belonging to the family Platanaceae, plane trees etc.
SANTALACEOUSsantalaceous adj. (Botany) Relating to the flowering plant family Santalaceae.
SANTALACEOUS adj. belonging to the sandalwood genus Santalum, or sandalwood family Santalaceae.
SARCOLEMMATAsarcolemmata n. Plural of sarcolemma.
SARCOLEMMA n. the cell membrane enclosing a muscle fibre.
SCARABAEOIDSscarabaeoids n. Plural of scarabaeoid.
SCARABAEOID n. any of various kinds of lamellicorn beetle, esp. Scarabaeus sacer (sacred scarab), regarded by the ancient Egyptians as divine.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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