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There are 8 twelve-letter words containing 3A, C, L and 2S

ACATALEPSIESACATALEPSY n. the sceptic doctrine that knowledge cannot be certain.
CRASSULACEANcrassulacean adj. (Botany) Of or pertaining to the family Crassulaceae of dicotyledons.
CRASSULACEAN adj. as in crassulacean acid metabolism, a method of photosynthesis.
MALFEASANCESmalfeasances n. Plural of malfeasance.
MALFEASANCE n. the performance by a public official of an act that is legally unjustified, harmful, or contrary to law; wrongdoing (used especially of an act in violation of a public trust), also MISFEASANCE.
PASSACAGLIASpassacaglias n. Plural of passacaglia.
PASSACAGLIA n. (Italian) an old slow Italian or Spanish dance; variations on a theme over a continuously repeated ground bass.
SACRAMENTALSsacramentals n. Plural of sacramental.
SACRAMENTAL n. an action or object, such as the rosary, of ecclesiastical origin that serves to express or increase devotion.
SANTALACEOUSsantalaceous adj. (Botany) Relating to the flowering plant family Santalaceae.
SANTALACEOUS adj. belonging to the sandalwood genus Santalum, or sandalwood family Santalaceae.
THALASSAEMICthalassaemic adj. Alternative form of thalassemic.
thalassaemic n. Alternative form of thalassemic.
THALASSAEMIC n. a person who has the blood disorder thalassaemia.
THALASSOCRATthalassocrat n. One who rules over the sea.
THALASSOCRAT n. one who has maritime supremacy.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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