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There are 10 twelve-letter words containing 2A, G, 2M and 2S

ASTIGMATISMSastigmatisms n. Plural of astigmatism.
ASTIGMATISM n. a defect in the eye or a lens by which rays from a single source are not focused at a single point, also ASTIGMIA.
CHASMOGAMIESCHASMOGAMY n. the opening of a flower in order to be fertilized.
CHASMOGAMOUSchasmogamous adj. Exhibiting chasmogamy.
CHASMOGAMOUS adj. relating to chasmogamy, the opening of a flower in order to be fertilized, also CHASMOGAMIC.
GAMESMANSHIPgamesmanship n. The use of legal but unsporting tactics to gain an advantage over one’s opponent.
GAMESMANSHIP n. the art or practice of winning games by questionable expedients without actually violating the rules.
GAMMERSTANGSgammerstangs n. Plural of gammerstang.
GAMMERSTANG n. (dialect) a tall, awkward person, usually a woman.
MAMMALOGISTSmammalogists n. Plural of mammalogist.
MAMMALOGIST n. a student of mammals.
MARGINALISMSmarginalisms n. Plural of marginalism.
MARGINALISM n. an economic theory that the value of a product depends on its value to the final consumer.
MEGASTARDOMSSorry, definition not available.
MISMARRIAGESmismarriages n. Plural of mismarriage.
MISMARRIAGE n. an unsuitable marriage.
PLASMOGAMIESPLASMOGAMY n. a process of fusion of the cytoplasm of two cells; the first step in syngamy, also PLASTOGAMY.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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