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There are 2 twelve-letter words containing 2A, O, P, S and 2U

AMPULLACEOUSampullaceous adj. Shaped like a swollen bottle.
AMPULLACEOUS adj. of or like an ampulla, also AMPULLACEAL.
UPVALUATIONSUPVALUATION n. the act of upvaluing.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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