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There are 2 twelve-letter words containing A, E, O, 3T and X

EXTORTIONATEextortionate adj. Of, related to, or typifying extortion (“the practice of obtaining money or other property by the use…
extortionate adj. Greatly exceeding what is moderate or reasonable; exorbitant.
EXTORTIONATE adj. characterized by extortion.
METHOTREXATEmethotrexate n. (Pharmacology) An antimetabolite and antifolate drug used in treatment of cancer and autoimmune diseases.
METHOTREXATE n. a drug used in the treatment of cancer.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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