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There are 3 twelve-letter words containing A, M, N, 2O, P and Z

OPTIMIZATIONoptimization n. The design and operation of a system or process to make it as good as possible in some defined sense.
optimization n. (Programming) The reduction of a program or algorithm to its most efficient form, as during compilation…
OPTIMIZATION n. the act of optimizing, also OPTIMISATION.
SPERMATOZOANspermatozoan adj. Of or pertaining to spermatozoa.
spermatozoan n. A spermatozoon.
SPERMATOZOAN n. a male sex cell, also SPERMATOZOON.
SPERMATOZOONspermatozoon n. (Cytology) A reproductive cell or gamete of a male, carried in semen, that fertilizes an ovum to produce a zygote.
spermatozoön n. Alternative spelling of spermatozoon.
SPERMATOZOON n. a male sexual cell, which fertilises the egg, also SPERMATOZOAN.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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