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There are 2 eight-letter words containing 2A, G, I, M, S and T

ASTIGMIAastigmia n. Astigmatism.
ASTIGMIA n. a defect in the eye or a lens by which rays from a single source are not focused at a single point, also ASTIGMATISM.
STIGMATAstigmata n. Plural of stigma.
Stigmata prop.n. (Religion, Christianity) bodily marks or sores, corresponding in location to the crucifixion wounds…
STIGMA n. (Latin) a mark of disgrace.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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