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There are 2 eight-letter words containing A, D, 2E, G, O and S

DOGEATESdogeates n. Plural of dogeate.
DOGEATE n. the office of a doge, or chief magistrate of Venice, also DOGESHIP, DOGATE.
MEGADOSEmegadose n. A dose of drug or vitamin far exceeding the normal or recommended amount, and usually given intentionally…
megadose v. (Transitive) To dose (a patient) with a very large amount of a drug.
megadose v. (Transitive) To dose with a very large amount of (a drug).

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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