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There are 3 eight-letter words containing A, D, 2I, P and 2S

ADIPOSISadiposis n. (Medicine) A condition marked by the accumulation of adipose (fatty) tissue.
ADIPOSIS n. obesity.
ADIPSIASadipsias n. Plural of adipsia.
ADIPSIA n. complete lack of thirst.
DIAPSIDSdiapsids n. Plural of diapsid.
DIAPSID n. a diapsid reptile.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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