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There are 4 eight-letter words containing A, E, I, 2L, O and S

ISOLABLEisolable adj. Able to be isolated.
ISOLABLE adj. capable of being isolated, or of being obtained in a pure state; as, gold is isolable.
LOBELIASlobelias n. Plural of lobelia.
LOBELIA n. a flowering plant.
LOCALISElocalise v. (British spelling, transitive) alternative spelling of localize.
LOCALISE v. to confine or limit to a certain place, also LOCALIZE.
LOESSIALloessial adj. (Geology) Of or relating to loess.
LOESSIAL adj. relating to loess, a fine-grained wind deposit of clay, sand, and silt, also LOESSAL, LOESSIC.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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