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There are 7 eight-letter words containing A, I, M, O, S and 2T

ATOMISTSatomists n. Plural of atomist.
ATOMIST n. an adherent of atomism, the belief that the universe consists of small indivisible particles.
MASTICOTmasticot n. Obsolete form of massicot.
MASTICOT n. (French) yellow lead monoxide, also MASSICOT.
MATTOIDSmattoids n. Plural of mattoid.
MATTOID n. a person on the borderline between sanity and insanity.
SOMATISTsomatist n. One who admits the existence of material beings only; a materialist.
SOMATIST n. one who admits the existence of material beings only; a materialist.
STOMATICstomatic adj. Stomatal.
stomatic n. (Medicine, archaic) A medicine for diseases of the mouth.
STOMATIC adj. of or pertaining to a stoma; of the nature of a stoma.
TOTALISMtotalism n. (Rare, usually uncountable) A social, economic and/or political system in which some authority (e.g…
totalism n. (Rare, countable) A philosophy, ideology or belief system that is total in its scope, one that covers everything.
totalism n. (Rare, uncountable) Totality; (the) entirety (of something).
TRITOMAStritomas n. Plural of tritoma.
TRITOMA n. a flowering African plant, aka kniphofia.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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