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There are 16 words containing 2A, C, D, 2F and I

AFFIANCEDaffianced v. Simple past tense and past participle of affiance.
affianced adj. (Literary) engaged; betrothed.
AFFIANCE v. to betroth.
FAIRFACEDFAIRFACED adj. of bricks, with a smooth unplastered surface.
AFFRICATEDaffricated v. Simple past tense and past participle of affricate.
AFFRICATE v. to sound a consonant in this way.
AFFICIONADOafficionado n. Alternative spelling of aficionado (“one who likes, knows about, and appreciates an interest”).
AFFICIONADO n. (Spanish) a devotee, admirer, an enthusiastic fan, also AFICIONADO.
CAFFEINATEDcaffeinated adj. Containing caffeine naturally (e.g., coffee, tea, and cacao) or as an additive (e.g., soft drinks, sports…
caffeinated adj. (Informal, of a person) Overly peppy or energetic; stimulated by caffeine.
caffeinated v. Simple past tense and past participle of caffeinate.
AFFICIONADOSafficionados n. Plural of afficionado.
AFFICIONADO n. (Spanish) a devotee, admirer, an enthusiastic fan, also AFICIONADO.
AFFRANCHISEDaffranchised v. Simple past tense and past participle of affranchise.
AFFRANCHISE v. to free from slavery or similar obligation.
DECAFFEINATEdecaffeinate v. (Transitive) To remove the caffeine from something (especially from coffee).
DECAFFEINATE v. to remove caffeine from.
DECAFFEINATEDdecaffeinated adj. From which caffeine has been removed (e.g. decaffeinated coffee).
DECAFFEINATE v. to remove caffeine from.
DECAFFEINATESdecaffeinates v. Third-person singular simple present indicative form of decaffeinate.
DECAFFEINATE v. to remove caffeine from.
DIEFFENBACHIAdieffenbachia n. Any of several plants, of the genus Dieffenbachia, cultivated as houseplants.
Dieffenbachia prop.n. A taxonomic genus within the family Araceae – the mother-in-law’s tongue, dumb cane and similar plants.
DIEFFENBACHIA n. any plant of the tropical American araceous genus Dieffenbachia, including the dumbcane.
DISAFFIRMANCEdisaffirmance n. (Law) The act of disaffirming; denial.
disaffirmance n. (Law) Overthrow or annulment by the decision of a superior tribunal.
DISAFFIRMANCE n. the act of disaffirming.
DECAFFEINATINGdecaffeinating v. Present participle of decaffeinate.
DECAFFEINATE v. to remove caffeine from.
DIEFFENBACHIASdieffenbachias n. Plural of dieffenbachia.
DIEFFENBACHIA n. any plant of the tropical American araceous genus Dieffenbachia, including the dumbcane.
DISAFFIRMANCESdisaffirmances n. Plural of disaffirmance.
DISAFFIRMANCE n. the act of disaffirming.
DISAFFECTIONATEdisaffectionate adj. Not disposed to affection; unfriendly.
DISAFFECTIONATE adj. showing disaffection.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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