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There are 9 words containing 2A, D, 2E, F and U

SAFEGUARDEDsafeguarded v. Simple past tense and past participle of safeguard.
safe-guarded v. Simple past tense and past participle of safe-guard.
SAFEGUARD v. to keep safe.
UNDEFEATABLEundefeatable adj. Not defeatable; impossible to defeat.
undefeatable n. Something that has an undefeatable quality.
UNDEFEATABLE adj. not able to be defeated.
SULFACETAMIDEsulfacetamide n. (Pharmacology) A sulfonamide antibiotic.
sulfacetamide n. (Organic chemistry) The amide of sulfacetic acid.
SULFACETAMIDE n. a sulphonamide used in eye drops against conjunctivitis, etc., also SULPHACETAMIDE.
ULTRARAREFIEDultrararefied adj. Very highly rarefied.
ULTRARAREFIED adj. exceptionally rarefied.
REMANUFACTUREDremanufactured v. Simple past tense and past participle of remanufacture.
remanufactured adj. Having the property of having undergone remanufacture.
REMANUFACTURE v. to manufacture into a new product.
SULFACETAMIDESSULFACETAMIDE n. a sulphonamide used in eye drops against conjunctivitis, etc., also SULPHACETAMIDE.
FUNDAMENTALNESSfundamentalness n. The state or condition of being fundamental; essential importance.
FUNDAMENTAL n. basic.
PREMANUFACTUREDpremanufactured v. Simple past tense and past participle of premanufacture.
PREMANUFACTURE v. to manufacture in advance.
UNSTEADFASTNESSunsteadfastness n. The quality of being unsteadfast.
UNSTEADFASTNESS n. the state of being unsteadfast.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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