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There are 12 fifteen-letter words containing 2A, D, 2E, M, O and S

ADRENALECTOMIESadrenalectomies n. Plural of adrenalectomy.
ADRENALECTOMY n. the surgical removal of the adrenal glands.
AMINOPEPTIDASESaminopeptidases n. Plural of aminopeptidase.
AMINOPEPTIDASE n. an enzyme.
DEMAGNETISATIONdemagnetisation n. (British spelling) Alternative form of demagnetization.
DEMAGNETISATION n. the act of demagnetising, also DEMAGNETIZATION.
DERMATOGRAPHIESDERMATOGRAPHY n. anatomical description of the skin, also DERMOGRAPHY.
DERMATOPLASTIESdermatoplasties n. Plural of dermatoplasty.
DERMATOPLASTY n. a plastic operation on the skin.
DEUTERANOMALIESdeuteranomalies n. Plural of deuteranomaly.
DEUTERANOMALY n. the state of being deuteranomalous.
DEUTERANOMALOUSdeuteranomalous adj. Having or relating to deuteranomaly.
DEUTERANOMALOUS adj. exhibiting partial loss of green color vision so that an increased intensity of green is required in a mixture of red and green to match a given yellow.
EUDAEMONISTICALEUDAEMONISTICAL adj. relating to eudaemonism, the theory that the highest ethical goal is happiness and personal wellbeing, also EUDAEMONISTIC, EUDEMONISTIC, EUDEMONISTICAL.
HAMAMELIDACEOUShamamelidaceous adj. (Botany) Belonging to the Hamamelidaceae.
HAMAMELIDACEOUS adj. belonging to the witch-hazel family.
HEXOSAMINIDASEShexosaminidases n. Plural of hexosaminidase.
HEXOSAMINIDASE n. either of two hydrolytic enzymes that catalyze the splitting off of a hexose from a ganglioside and are deficient in some metabolic diseases.
MALADROITNESSESmaladroitnesses n. Plural of maladroitness.
MALADROITNESS n. MALADROIT, (French) clumsy, unskilful.
TATTERDEMALIONStatterdemalions n. Plural of tatterdemalion.
TATTERDEMALION n. a person in ragged clothes, also TATTERDEMALLION.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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