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There are 20 fifteen-letter words containing 2A, D, 2I and 3S

BASTARDISATIONSbastardisations n. Plural of bastardisation.
BASTARDISATION n. the process of bastardising, also BASTARDIZATION.
DESALINISATIONSDESALINISATION n. the process of desalinising, also DESALINIZATION.
DISACCHARIDASESdisaccharidases n. Plural of disaccharidase.
DISACCHARIDASE n. an enzyme (as maltase or lactase) that hydrolyzes disaccharides.
DISASSIMILATINGdisassimilating v. Present participle of disassimilate.
DISASSIMILATE v. to subject to catabolism.
DISASSIMILATIONdisassimilation n. (Obsolete, biochemistry) catabolism (metabolism with the release of energy).
disassimilation n. The act of becoming less assimilated or integrated, particularly of ethnic groups.
DISASSIMILATION n. the act of disassimilating, subjecting to catabolism.
DISASSIMILATIVEdisassimilative adj. (Physiology) Having power to disassimilate; of the nature of disassimilation.
DISASSIMILATIVE adj. relating to the act of dissimilation, subjecting to catabolism.
DISASSOCIATIONSdisassociations n. Plural of disassociation.
DISASSOCIATION n. the act of disassociating.
DISEMBARRASSINGdisembarrassing v. Present participle of disembarrass.
DISEMBARRASS v. to free from something troublesome or superfluous.
DISPASSIONATELYdispassionately adv. In a dispassionate manner.
DISPASSIONATE adv. not influenced by strong feeling.
DISSATISFACTIONdissatisfaction n. Unhappiness or discontent.
dissatisfaction n. The cause of such feelings.
DISSATISFACTION n. the state of being dissatisfied.
DISSATISFACTORYdissatisfactory adj. Causing dissatisfaction.
DISSATISFACTORY adj. causing dissatisfaction.
ENDOPARASITISMSendoparasitisms n. Plural of endoparasitism.
ENDOPARASITISM n. the state of being an endoparasite, a parasite that lives inside an animal.
HEXOSAMINIDASEShexosaminidases n. Plural of hexosaminidase.
HEXOSAMINIDASE n. either of two hydrolytic enzymes that catalyze the splitting off of a hexose from a ganglioside and are deficient in some metabolic diseases.
INADVISABLENESSinadvisableness n. Inadvisability; the state or quality of being inadvisable.
INADVISABLE n. not advisable.
SADOMASOCHISTICsadomasochistic adj. Of or relating to sadomasochism or sadomasochists.
SADOMASOCHISTIC adj. relating to sadomasochism.
SCANDALISATIONSscandalisations n. Plural of scandalisation.
SCANDALISATION n. the process of scandalising, also SCANDALIZATION.
SENSATIONALISEDsensationalised v. Simple past tense and past participle of sensationalise.
SENSATIONALISE v. to make (an event, situation, etc.) appear more exciting or shocking than it really is, also SENSATIONALIZE.
SESQUIPEDALIANSsesquipedalians n. Plural of sesquipedalian.
SESQUIPEDALIAN n. a polysyllabic word, also SESQUIPEDAL.
SHERARDISATIONSSHERARDISATION n. the process of sherardising, also SHERARDIZATION.
SUBSTANTIALISEDsubstantialised v. Simple past tense and past participle of substantialise.
SUBSTANTIALISE v. to make substantial, also SUBSTANTIALIZE.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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