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There are 20 fifteen-letter words containing 2A, 3E, M, S and T

ADRENALECTOMIESadrenalectomies n. Plural of adrenalectomy.
ADRENALECTOMY n. the surgical removal of the adrenal glands.
AFTERTREATMENTSAFTERTREATMENT n. additional treatment that is given to a patient following an illness or medical procedure.
DEPARTMENTALISEdepartmentalise v. Alternative spelling of departmentalize.
DEPARTMENTALISE v. to form into separate departments, also DEPARTMENTALIZE.
DEUTERANOMALIESdeuteranomalies n. Plural of deuteranomaly.
DEUTERANOMALY n. the state of being deuteranomalous.
DEXAMPHETAMINESDEXAMPHETAMINE n. the dextrorotatory isomer of amphetamine, used as a stimulant.
ELEUTHEROMANIASELEUTHEROMANIA n. a manic desire for freedom.
HAEMACYTOMETERShaemacytometers n. Plural of haemacytometer.
HAEMACYTOMETER n. an apparatus for counting the number of cells in a quantity of blood, typically consisting of a graduated pipette for drawing and diluting, also HEMACYTOMETER.
HEADMASTERLIESTHEADMASTERLY adj. like a headmaster.
HEMOFLAGELLATEShemoflagellates n. Plural of hemoflagellate.
HEMOFLAGELLATE n. a flagellate (as a trypanosome) that is a blood parasite, also HAEMOFLAGELLATE.
INANIMATENESSESinanimatenesses n. Plural of inanimateness.
INANIMATENESS n. the state of being inanimate.
MEGAVERTEBRATESmegavertebrates n. Plural of megavertebrate.
MEGAVERTEBRATE n. a very large vertebrate.
MESATICEPHALIESMESATICEPHALY n. the state of being mesaticephalic.
OVERMANAGEMENTSSorry, definition not available.
PERGAMENTACEOUSpergamentaceous adj. (Biology, now chiefly botany) Reminiscent of parchment.
PERGAMENTACEOUS adj. parchment-like, also PERGAMENEOUS.
PREARRANGEMENTSprearrangements n. Plural of prearrangement.
PREARRANGEMENT n. a preliminary arrangement.
REAPPRAISEMENTSREAPPRAISEMENT n. the act of reappraising.
SHAMEFASTNESSESSHAMEFASTNESS n. SHAMEFAST, modest, bashful, also SHAMEFACED.
THERMAESTHESIASTHERMAESTHESIA n. sensitivity to various degrees of heat and cold, also THERMESTHESIA.
UNTAMABLENESSESUNTAMABLENESS n. the state of being untamable, also UNTAMEABLENESS.
WARMHEARTEDNESSwarmheartedness n. The quality of being warmhearted.
warm-heartedness n. The quality of being warm-hearted.
WARMHEARTEDNESS n. the state of being warmhearted.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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