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There are 11 words containing 2A, D, E, F, 2S and U

SAFEGUARDSsafeguards n. Plural of safeguard.
safeguards v. Third-person singular simple present indicative form of safeguard.
safe-guards v. Third-person singular simple present indicative form of safe-guard.
UNSTEADFASTunsteadfast adj. Not steadfast; wavering, unfaithful.
UNSTEADFAST adj. not steadfast.
SULFADIAZINESsulfadiazines n. Plural of sulfadiazine.
SULFADIAZINE n. a sulfa drug used esp. in the treatment of toxoplasmosis.
UNSTEADFASTLYunsteadfastly adv. In an unsteadfast manner.
UNSTEADFAST adv. not steadfast.
FEUDALISATIONSfeudalisations n. Plural of feudalisation.
FEUDALISATION n. the act of feudalising, also FEUDALIZATION.
SULFACETAMIDESSULFACETAMIDE n. a sulphonamide used in eye drops against conjunctivitis, etc., also SULPHACETAMIDE.
SULFANILAMIDESsulfanilamides n. Plural of sulfanilamide.
SULFANILAMIDE n. a crystalline sulfonamide that is the parent compound of most of the sulfa drugs.
FUNDAMENTALISMSfundamentalisms n. Plural of fundamentalism.
FUNDAMENTALISM n. a movement in 20th century Protestantism emphasizing the literally interpreted Bible as fundamental to Christian life and teaching.
FUNDAMENTALISTSfundamentalists n. Plural of fundamentalist.
FUNDAMENTALIST n. an exponent of fundamentalism.
FUNDAMENTALNESSfundamentalness n. The state or condition of being fundamental; essential importance.
FUNDAMENTAL n. basic.
UNSTEADFASTNESSunsteadfastness n. The quality of being unsteadfast.
UNSTEADFASTNESS n. the state of being unsteadfast.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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