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There are 20 fourteen-letter words containing A, D, E, F, 2I, R and S

ANTIFEDERALISTantifederalist n. Alternative spelling of anti-federalist.
anti-federalist n. One who opposes federalism.
anti-federalist adj. Opposing federalism.
ARTIFICIALISEDartificialised v. Simple past tense and past participle of artificialise.
ARTIFICIALISE v. to make artificial, also ARTIFICIALIZE.
DEFAMILIARIZESdefamiliarizes v. Third-person singular simple present indicative form of defamiliarize.
DEFIBRILLATORSdefibrillators n. Plural of defibrillator.
DEFIBRILLATOR n. an electronic device that applies an electric shock to restore the rhythm of a fibrillating heart.
DEFIBRINATIONSdefibrinations n. Plural of defibrination.
DEFIBRINATION n. the act of defibrinating.
DELIRIFACIENTSdelirifacients n. Plural of delirifacient.
DELIRIFACIENT n. a substance producing or creating delirium.
DIAMANTIFEROUSdiamantiferous adj. Yielding diamonds.
DIAMANTIFEROUS adj. bearing diamonds.
DIAMONDIFEROUSdiamondiferous adj. (Mineralogy) Yielding diamond.
DIAMONDIFEROUS adj. containing diamonds.
DIFFARREATIONSDIFFARREATION n. (historical) a Roman form of divorce.
DIFFERENTIATESdifferentiates v. Third-person singular simple present indicative form of differentiate.
DIFFERENTIATE v. to obtain the mathematical derivative of.
DISAFFIRMANCESdisaffirmances n. Plural of disaffirmance.
DISAFFIRMANCE n. the act of disaffirming.
DISAFFORESTINGdisafforesting v. Present participle of disafforest.
DISAFFOREST v. to clear of forest, also DISFOREST.
DISENFRANCHISEdisenfranchise v. (Transitive) To deprive someone of a franchise, generally of the right to vote.
DISENFRANCHISE v. to deprive of a franchise.
DISFORESTATIONdisforestation n. Archaic form of deforestation.
DISFORESTATION n. the act of disforesting.
FEDERALISATIONfederalisation n. Non-Oxford British spelling standard spelling of federalization.
FEDERALISATION n. the process of federalising, also FEDERALIZATION.
FRACTIONALISEDfractionalised v. Simple past tense and past participle of fractionalise.
FRACTIONALISE v. to break up into parts, also FRACTIONALIZE.
OVERCLASSIFIEDoverclassified v. Simple past tense and past participle of overclassify.
OVERCLASSIFY v. to classify to excess.
OVERFASTIDIOUSoverfastidious adj. Excessively fastidious.
OVERFASTIDIOUS adj. excessively fastidious.
TRANSMOGRIFIEDtransmogrified v. Simple past tense and past participle of transmogrify.
transmogrified adj. Altered, transformed, or mutated into a form that is grotesque or amusing.
TRANSMOGRIFY v. to change or alter greatly and often with grotesque or humorous effect.
UNTHRIFTIHEADSUNTHRIFTIHEAD n. (archaic) thriftlessness.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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