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There are 12 words containing A, 2D, 2E, 2M and S

CHORDAMESODERM	• chordamesoderm n. (Anatomy) The axial mesoderm, which lies along the central axis under the neural tube and gives rise to the notochord. • CHORDAMESODERM n. the layer of specialized cells in the middle of a developing embryo which forms the notochord and structures of the central nervous system.
CHORDAMESODERMS	• CHORDAMESODERM n. the layer of specialized cells in the middle of a developing embryo which forms the notochord and structures of the central nervous system.
DEMIMONDAINES	• demimondaines n. Plural of demimondaine. • demi-mondaines n. Plural of demi-mondaine. • DEMIMONDAINE n. (French) a demirep, a woman of doubtful reputation.
DISCOMMENDABLE	• discommendable adj. Deserving disapprobation or blame. • DISCOMMENDABLE adj. that can be discommended.
DUMMELHEADS	• DUMMELHEAD n. (dialect) a stupid person.
LAMPADEDROMIES	• LAMPADEDROMY n. a foot race with lighted torches, esp. a relay race in which the torch is passed on, also LAMPADEPHORIA.
MALADMINISTERED	• maladministered v. Simple past tense and past participle of maladminister. • MALADMINISTER v. to administer wrongly.
MASTERMINDED	• masterminded v. Simple past tense and past participle of mastermind. • MASTERMIND v. to originate, think out, and direct.
MELODRAMATISED	• melodramatised v. Simple past tense and past participle of melodramatise. • MELODRAMATISE v. to make melodramatic, also MELODRAMATIZE.
MIDDLEGAMES	• middlegames n. Plural of middlegame. • middle␣games n. Plural of middle game.
MISDEMEANED	• misdemeaned v. Simple past tense and past participle of misdemean. • MISDEMEAN v. to behave ill, with a reflexive pronoun; as, to misdemean one's self.
SLEDGEHAMMERED	• sledgehammered v. Simple past tense and past participle of sledgehammer. • SLEDGEHAMMER v. to strike with a sledgehammer.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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English Wiktionary: 203 words
Scrabble in French: 41 words
Scrabble in Spanish: 104 words
Scrabble in Italian: 36 words
Scrabble in German: 1 word
Scrabble in Romanian: 12 words

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