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There are 12 five-letter words containing C, D, E and U

CLUEDclued v. Simple past tense and past participle of clue.
CLUE v. to obtain guiding information.
COUDEcoudé adj. (Of a catheter) Bent at the tip at a 45° angle, like an elbow.
COUDE n. (French) a reflecting telescope in which one or more plane mirrors reflects the light down the polar axis.
CRUDEcrude adj. In a natural, untreated state.
crude adj. Characterized by simplicity, especially something not carefully or expertly made.
crude adj. Lacking concealing elements.
CUBEDcubed v. Simple past tense and past participle of cube.
cubed adj. (Mathematics) Raised to the third power.
CUBE v. to raise to the third power.
CUREDcured v. Simple past tense and past participle of cure.
CURE v. to restore to health.
DEUCEdeuce n. (Card games) A card with two pips, one of four in a standard deck of playing cards.
deuce n. (Dice games) A side of a die with two spots.
deuce n. (Dice games) A cast of dice totalling two.
DOUCEdouce adj. (Obsolete) Sweet; nice; pleasant.
douce adj. (Dialect) Serious and quiet; steady, not flighty or casual; sober.
DOUCE adj. (French) sweet, pleasant.
DUCESduces n. Plural of dux.
Duces prop.n. Plural of Duce.
DUCE n. (Italian) a leader.
DULCEdulce adj. (Obsolete) sweet.
dulce n. (Obsolete) sweetness.
dulce v. (Obsolete, transitive) To make sweet; to soothe.
DUNCEdunce n. An unintelligent person.
DUNCE n. a stupid person.
EDUCEeduce v. (Transitive, now rare) To direct the course of (A flow, journey etc.); to lead in a particular direction.
educe v. (Transitive) To infer or deduce (A result, theory etc.) from existing data or premises.
educe v. (Transitive) To draw out or bring forth from some basic or potential state; to elicit, to develop.
EDUCTeduct n. That which is educed.
educt n. (Obsolete, chemistry) A reactant.
educt v. (Engineering) To educe, to extract.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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