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There are 12 five-letter words containing C, I, O and T

COATIcoati n. Any of several omnivorous mammals, of the genus Nasua or Nasuella, in order Carnivora, that live in…
COATI n. (Tupi) a tropical American carnivorous mammal related to the raccoon, also COATIMUNDI.
COITScoits n. Plural of coit.
coits v. Third-person singular simple present indicative form of coit.
Coits prop.n. Plural of Coit.
DICOTdicot n. (Botany) A plant whose seedlings have two cotyledons, a dicotyledon.
DICOT n. (short for) a dicotyledon, a plant having two cotyledons, seed-leaves, also DICOTYL.
LOTIClotic adj. Characterised by flowing water; swiftly flowing; concerned with flowing rivers, streams, etc.
lotic adj. (Biology) Living in flowing water; adapted to life in flowing water.
LOTIC adj. pertaining to moving water.
ONTIContic adj. Ontological.
ontic adj. Pertaining to being generally, as opposed to some theory of it (which would be ontology).
ONTIC adj. having real existence.
OPTICoptic adj. (Relational) Of, or relating to the eye or to vision.
optic adj. (Optics, relational) Of, or relating to optics or optical instruments.
optic n. (Archaic, humorous) An eye.
PICOTpicot n. An embroidery trim made of a series of small loops.
PICOT v. (French) to edge with ornamental loops.
STOICstoic n. (Philosophy) Proponent of stoicism, a school of thought, from in 300 B.C.E. up to about the time of…
stoic n. A person indifferent to pleasure or pain.
stoic adj. Of or relating to the Stoics or their ideas.
TONICtonic adj. (Physics, pathology) Pertaining to tension, especially of muscles.
tonic adj. Restorative, curative or invigorating.
tonic adj. (Medicine, neuroscience) In a state of continuous unremitting action.
TOPICtopic adj. Topical.
topic n. Subject; theme; a category or general area of interest.
topic n. (Internet) Discussion thread.
TORICtoric adj. Pertaining to or shaped like a torus, or a section of a torus; toroidal.
TORIC adj. having the form of a torus, a rounded swelling.
TORIC n. a torus, a rounded swelling.
TOXICtoxic adj. (Toxicology, pharmacology) Having a chemical nature that is harmful to health or lethal if consumed…
toxic adj. (Medicine) Appearing grossly unwell; characterised by serious, potentially life-threatening compromise…
toxic adj. (Figurative) Severely negative or harmful.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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