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There are 20 twelve-letter words containing C, I, Q, R and S

ACQUIREMENTSacquirements n. Plural of acquirement.
ACQUIREMENT n. a skill of mind or body usually resulting from continued endeavor.
AQUICULTURESaquicultures n. Plural of aquiculture.
AQUICULTURE n. the practice of using the sea, lakes etc. for fish-farming, also AQUACULTURE.
BIQUADRATICSbiquadratics n. Plural of biquadratic.
BIQUADRATIC n. a quantity twice squared, or raised to the fourth power.
CHIVALRESQUEchivalresque adj. Characteristic of chivalry.
CHIVALRESQUE adj. relating to or connected with chivalry.
CHLOROQUINESchloroquines n. Plural of chloroquine.
CHLOROQUINE n. a drug used to suppress malaria, also CHLOROQUIN.
CONQUISTADORconquistador n. A conqueror, but especially one of the Spanish soldiers that invaded Central and South America otherwise…
CONQUISTADOR n. (Spanish) a conqueror; specifically any of the Spanish conquerors of Mexico and Peru in the 16th cent.
COREQUISITEScorequisites n. Plural of corequisite.
COREQUISITE n. a formal course of study required to be taken simultaneously with another.
CROQUIGNOLESCROQUIGNOLE n. a method used in waving the hair by winding it on curlers from the ends of the hair toward the scalp.
EQUIVOCATORSequivocators n. Plural of equivocator.
EQUIVOCATOR n. one who equivocates.
INFREQUENCESinfrequences n. Plural of infrequence.
INFREQUENCE n. rarity of occurrence, also INFREQUENCY.
PREACQUAINTSpreacquaints v. Third-person singular simple present indicative form of preacquaint.
PREACQUAINT v. to acquaint beforehand.
QUADRASONICSQUADRASONICS n. a system of sound recording and reproduction that uses four independent loudspeakers to give directional sources of sound.
QUADRATRICESquadratrices n. Plural of quadratrix.
QUADRATRIX n. a curve by which a circle may be squared.
QUADRICEPSESquadricepses n. Plural of quadriceps.
QUADRICEPS n. the great extensor muscle of the knee, divided above into four parts which unite in a single tendon at the knee.
QUADRISECTEDquadrisected v. Simple past tense and past participle of quadrisect.
QUADRISECT v. to divide into four equal parts.
QUASICRYSTALquasicrystal n. (Physics, chemistry) any solid with conventional crystalline properties but exhibiting a point group…
quasi-crystal n. Alternative form of quasicrystal.
QUASICRYSTAL n. a body of solid material that resembles a crystal in being composed of repeating structural units but that incorporates two or more unit cells into a quasiperiodic structure.
QUICKSILVERSquicksilvers v. Third-person singular simple present indicative form of quicksilver.
QUICKSILVER n. an old name for mercury.
QUICKSILVERYquicksilvery adj. Like quicksilver.
QUICKSILVERY adj. like quicksilver.
SQUIRARCHIESsquirarchies n. Plural of squirarchy.
SQUIRARCHY n. squires collectively, also SQUIRAGE, SQUIRALITY, SQUIRALTY, SQUIREAGE, SQUIREARCHY.
SQUIREARCHALsquirearchal adj. Of or pertaining to squirearchy.
SQUIREARCHAL adj. relating to a squirearchy, also SQUIRARCHAL, SQUIRARCHICAL, SQUIREARCHICAL.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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