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There are 2 five-letter words containing C, E, I, N and R

CRINE-crine suff. (Pharmacology) Used to form names of acridine derivatives.
CRINE v. (Scots) to shrink or shrivel.
NICERnicer adj. Comparative form of nice: more nice.
nicer adv. Comparative form of nice: more nice.
NICER prop.n. Initialism of w:Neutron Star Interior Composition Explorer, a future NASA Explorers program Mission of Opportunity.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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