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There are 7 eight-letter words containing 2C, I and 2U

ACICULUMaciculum n. (Botany, zoology) A needlelike spine or bristle, specially the seta of an annelid.
ACICULUM n. (Latin) a bristlelike part.
CUBICULAcubicula n. Plural of cubiculum.
CUBICULUM n. (Latin) a burial chamber.
CUCURBITcucurbit n. Any member of the family Cucurbitaceae of gourds.
cucurbit n. (Obsolete) A receptacle, originally gourd-shaped and used for liquids or chemicals; a bottle or other container.
CUCURBIT n. a chemical vessel used in a still or alembic.
CURCULIOcurculio n. Any of the genus Curculio of weevils.
Curculio prop.n. A taxonomic genus within the family Curculionidae.
CURCULIO n. (Latin) a kind of weevil.
CURCUMINcurcumin n. (Chemistry) A polyphenol (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione; a major…
CURCUMIN n. the saffron-yellow colouring matter of turmeric, used esp. in food colouring, also CURCUMINE.
CURLICUEcurlicue n. A fancy twisting or curling shape usually made from a series of spirals and loops.
curlicue v. (Transitive and intransitive) To make or adorn (something) with curlicues, or as if with curlicues.
CURLICUE v. to decorate with fancy spiral figures, also CURLYCUE.
CUTICULAcuticula n. (Zoology, botany) A tough protective covering outside the epidermis of many invertebrates and plants; cuticle.
CUTICULA n. (Latin) the outer hard covering of an insect.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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