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There are 15 twelve-letter words containing C, F, I, O and 2U

CAULIFLOROUScauliflorous adj. (Botany) Having flowers on the stem.
CAULIFLOROUS adj. relating to cauliflory, the production of flowers on old stems from dormant buds.
CIRCUMFLUOUScircumfluous adj. Circumfluent.
CIRCUMFLUOUS adj. flowing around, also CIRCUMFLUENT.
CIRCUMFUSIONcircumfusion n. Diffusion, suffusion.
CIRCUMFUSION n. the act of circumfusing, pouring around.
COUCHSURFINGcouchsurfing n. Alternative form of couch surfing.
couch-surfing n. Alternative form of couch surfing.
couch␣surfing n. The act or practice of an individual who couch surfs.
CUPULIFEROUScupuliferous adj. (Botany) Bearing, or furnished with, a cupule.
CUPULIFEROUS adj. bearing cupules.
FLORICULTUREfloriculture n. The farming of flowers.
FLORICULTURE n. the cultivation and management of ornamental and esp. flowering plants.
FLUCTUATIONSfluctuations n. Plural of fluctuation.
FLUCTUATION n. the act of fluctuating.
FLUOROURACILfluorouracil n. (Pharmacology) A fluorine-substituted derivative of uracil C4H3FN2O2 which inhibits DNA synthesis and…
FLUOROURACIL n. a fluorine-containing pyrimidine base used as a neoplastic agent to treat some kinds of cancer.
FRACTOCUMULIFRACTOCUMULUS n. a type of cloud.
FRUCTIFEROUSfructiferous adj. Bearing fruit.
FRUCTIFEROUS adj. bearing fruit.
FRUCTIVOROUSfructivorous adj. Fruit-eating.
FRUCTIVOROUS adj. feeding on fruit.
FRUCTUATIONSfructuations n. Plural of fructuation.
FRUCTUATION n. coming to fruit or bearing of fruit.
FURUNCULOSISfurunculosis n. (Medicine) The presence of furuncles or boils.
FURUNCULOSIS n. an affliction of boils.
SUFFRUTICOSEsuffruticose adj. (Botany) Having a woody base, but shrubby higher up.
SUFFRUTICOSE adj. of a perennial plant, having a woody base, but remaining herbaceous in upper part.
THIOSULFURICthiosulfuric adj. (Inorganic chemistry) Of or pertaining to thiosulfuric acid or its derivatives.
THIOSULFURIC adj. as in thiosulfuric acid, an unstable acid known only in solutions and in the form of its salts.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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