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There are 19 twelve-letter words containing C, F, L, R and 2U

CAULIFLOROUScauliflorous adj. (Botany) Having flowers on the stem.
CAULIFLOROUS adj. relating to cauliflory, the production of flowers on old stems from dormant buds.
CIRCUMFLUENTcircumfluent adj. Flowing round; surrounding in the manner of a fluid.
CIRCUMFLUENT adj. flowing round, also CIRCUMFLUOUS.
CIRCUMFLUOUScircumfluous adj. Circumfluent.
CIRCUMFLUOUS adj. flowing around, also CIRCUMFLUENT.
CIRCUMFUSILEcircumfusile adj. (Nonce word) Capable of being poured or spread around.
CIRCUMFUSILE adj. molten; poured around or about.
COUNTERBLUFFcounterbluff n. A bluff made in response to an opponent’s bluff; a counterploy.
COUNTERBLUFF n. actions or words intended as a bluff, made in opposition to someone else's bluff.
CUPULIFEROUScupuliferous adj. (Botany) Bearing, or furnished with, a cupule.
CUPULIFEROUS adj. bearing cupules.
FLORICULTUREfloriculture n. The farming of flowers.
FLORICULTURE n. the cultivation and management of ornamental and esp. flowering plants.
FLUOROURACILfluorouracil n. (Pharmacology) A fluorine-substituted derivative of uracil C4H3FN2O2 which inhibits DNA synthesis and…
FLUOROURACIL n. a fluorine-containing pyrimidine base used as a neoplastic agent to treat some kinds of cancer.
FRACTOCUMULIFRACTOCUMULUS n. a type of cloud.
FRAUDULENCESfraudulences n. Plural of fraudulence.
FRAUDULENCE n. the state of being fraudulent, also FRAUDULENCY.
FURUNCULOSESfurunculoses n. Plural of furunculosis.
FURUNCULOSIS n. an affliction of boils.
FURUNCULOSISfurunculosis n. (Medicine) The presence of furuncles or boils.
FURUNCULOSIS n. an affliction of boils.
MANUFACTURALmanufactural adj. Of or relating to manufacture.
MANUFACTURAL adj. relating to manufacture.
SCROFULOUSLYscrofulously adv. Morally degenerate; corrupt.
SCROFULOUS adv. afflicted with scrofula.
THIOSULFURICthiosulfuric adj. (Inorganic chemistry) Of or pertaining to thiosulfuric acid or its derivatives.
THIOSULFURIC adj. as in thiosulfuric acid, an unstable acid known only in solutions and in the form of its salts.
ULTRACAREFULultracareful adj. Extremely careful.
ULTRACAREFUL adj. very very careful.
UNCHEERFULLYuncheerfully adv. In a manner that is not cheerful.
UNCHEERFUL adv. not cheerful.
UNGRACEFULLYungracefully adv. In an ungraceful manner.
UNGRACEFUL adv. not graceful.
UNMERCIFULLYunmercifully adv. In an unmerciful manner.
UNMERCIFUL adv. not merciful.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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