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There are 8 eight-letter words containing C, D, M, N and 2O

CODOMAINcodomain n. (Mathematics, mathematical analysis) The target set into which a function is formally defined to map…
CODOMAIN n. in mathematics, the range, the set of output values of a function (the domain is the set of inputs).
COMEDOWNcomedown n. A sudden drop to a lower status, condition or level; a disappointment or letdown.
comedown n. A calm, mellow period experienced after the initial high from taking drugs.
come-down n. Alternative form of comedown.
COMMANDOcommando n. A small fighting force specially trained for making quick destructive raids against enemy-held areas.
commando n. A commando trooper.
commando n. (Historical) An organized force of Boer troops in South Africa; a raid by such troops.
COMMONEDcommoned v. Simple past tense and past participle of common.
COMMON v. to share.
COMPOUNDcompound n. An enclosure within which workers, prisoners, or soldiers are confined.
compound n. An enclosure for secure storage.
compound n. A group of buildings situated close together, e.g. for a school or block of offices.
DOWNCOMEdowncome n. A tumbling or falling down; a sudden or heavy fall; an overthrow; ruin; destruction.
downcome n. In ironmaking, a pipe that leads combustible gases downward from the top of the blast furnace to the…
downcome n. A downpour of rain.
MONOACIDmonoacid n. (Chemistry) Any acid that has only one replaceable hydrogen ion.
MONOACID n. a compound having one hydrogen atom replaceable by a negative or acid atom or radical, also MONACID.
MONOCLEDmonocled adj. Wearing a monocle.
MONOCLED adj. wearing a monocle.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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