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There are 5 ten-letter words containing C, 2E, H, 2M and S

EMPHYSEMICemphysemic adj. Relating to emphysema.
emphysemic n. A person who has emphysema.
EMPHYSEMIC n. a sufferer from emphysema.
HOMECOMERShomecomers n. Plural of homecomer.
HOMECOMER n. a person coming home.
MACHMETERSMachmeters n. Plural of Machmeter.
MACHMETER n. an instrument for measuring Mach number.
MEERSCHAUMmeerschaum n. (Uncountable) A soft white mineral, chiefly used for smoking-pipes and cigar holders.
meerschaum n. (Countable) A smoking-pipe made from meerschaum.
MEERSCHAUM n. (German) hydrated magnesium silicate occurring as a soft white or yellowish claylike mineral, aka sepiolite.
MESENCHYMEmesenchyme n. (Anatomy) That part of the mesoderm of an embryo that develops into connective tissue, bone, cartilage, etc.
MESENCHYME n. the embryonic tissue from which circulatory, lymphatic, skeletal, and connective tissue develop.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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