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There are 4 twelve-letter words containing 2C, F, R, S, T and U

CIRCUMFLECTScircumflects v. Third-person singular simple present indicative form of circumflect.
CIRCUMFLECT v. to bend round; to mark with a circumflex.
COSURFACTANTcosurfactant n. A surfactant acting in tandem with another surfactant to enhance its properties.
COSURFACTANT n. something that works in combination with a surfactant.
FLOCCULATORSflocculators n. Plural of flocculator.
FLOCCULATOR n. one who flocculates.
FRUTESCENCESFRUTESCENCE n. the appearance or habit of a shrub.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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